Sodium Chloride Injection 500ml

【Drug Name】

Common Name: Sodium Chloride Injection

Product name:Sodium Chloride Injection

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【?ingredients】

The main ingredients of this product and its chemical name: sodium chloride.

Chemical structural formula: NaCl

Molecular formula: NaCl

Molecular weight: 58.44

【Properties】

This product is a colorless clear liquid; the taste is slightly salty.

【indications】

Dehydration caused by various reasons, including hypotonicity, isotonicity and hypertonic water loss; hyperosmotic non-ketotic diabetic coma; low chloride metabolic alkalosis; topical saline flushing the eye, washing the wound Etc.; also used in the obstetrics of water bladder induction.

【Specifications】?(1) 500ml (2) 250ml (3) 100ml (4) 50ml

【Adverse reactions】

Generally no adverse reactions, improper application may have: (1) too fast, excessive blood pressure, headache, dizziness.?(2) Weight gain and edema.?(3) heart rate acceleration, chest tightness, difficulty breathing, lung wheezing.

【taboo】

(1) heart failure; (2) pulmonary edema; (3) cerebral edema, increased intracranial pressure; (4) cirrhosis ascites; (5) acute renal failure oliguria; chronic renal failure does not respond to diuretics Good; (6) hypernatremia

【Notes】

Use with caution in the following situations: (1) edema in pregnancy; (2) high blood pressure; (3) edema or edema tendency, especially those with high edema and hyponatremia; (4) mild heart, Renal insufficiency; (5) hypokalemia; (6) elderly with impaired heart function; (7) administration according to the nature of hypertonic, isotonic or hypotonic, and Consider mixing with other solutions to maintain a balanced relationship between the various electrolytes in the body.?(8) Follow-up examination of serum potassium, sodium, chlorine concentration, acid-base balance, cardiopulmonary and renal function, blood pressure and other indicators.

【Pregnant women and lactating women】gestational hypertension syndrome is banned.

【Children's medication】 The amount and speed of rehydration in children should be strictly controlled.

【Geriatric Use】 The amount and speed of rehydration in the elderly should be strictly controlled.

【medicine interactions】

(1) compatibility with amphotericin B, etc., turbidity or precipitation, discoloration; (2) contraindications with reserpine, polymyxin B sulfate, polymyxin E sulfate, cephalosporin I.

【Drug overdose】

Too much infusion, too fast, can cause sodium retention, causing edema, elevated blood pressure, increased heart rate, chest tightness, difficulty breathing, and even acute left heart failure.

【Pharmacology and Toxicology】

Sodium chloride is an electrolyte supplement.?Sodium and chlorine are important electrolytes in the body. They are mainly found in extracellular fluids and play an important role in maintaining normal blood and extracellular fluid volume and osmotic pressure.?Normal serum sodium concentration is 135 ~ 145mmol / L, accounting for 92% of plasma cations, 90% of total osmotic pressure, so the amount of plasma sodium plays a decisive role in osmotic pressure.?The normal serum chlorine concentration is 98-106mmol/L. The sodium and chloride ions in the human body are mainly regulated by the hypothalamus, the posterior pituitary and the kidney, and the body fluid volume and osmotic pressure are maintained.

【Pharmacokinetics】

Sodium chloride enters the blood circulation directly after intravenous injection and is widely distributed in the body, but mainly in the extracellular fluid.?Both sodium and chloride ions can be filtered by the glomerulus and partially reabsorbed by the renal tubules.?Excreted by the kidneys with the urine, only a small part is excreted from the sweat.

【Storage】?sealed and stored.

【Package】 non-PVC soft bag [pull ring, easy to fold (double valve)]: 500ml / bag × 20 bags; 250ml / bag × 40 bags; 100ml / bag × 80 bags; 50ml / bag × 80 bags.

【Validity period】 24 months.

【Executive Standards】 The second edition of the 2015 edition of the Chinese Pharmacopoeia.

【Approval number】

500ml: 4.5g Chinese medicine standard word H20113071	250ml: 2.25g Chinese medicine standard word H20113064
100ml: 0.9g Chinese medicine standard word H20113066	50ml: 0.45g Chinese medicine standard word H20113034

【Manufacturer】

Company Name: Zhejiang Kancheer Pharmaceutical Co., Ltd.

Production address: Beijiang Industrial Zone, Geshan Town, Dongyang City, Zhejiang Province, China

Website: tianshicheng.cn

Zip code: 322105

Tel: (0579) 86019696 86019610

Fax number: (0579) 86019611